Example dataset comparing two antibody responses against the first 35 sequences. Both antibodies interact strongly with WT RBD peptide #9 (RP9) and lose affinity when the K417N (Beta & Omicron) or K417T (Gamma) mutations are present.

Glycopeptides

Available Sequences

SARS-CoV-2 RBD Peptide and Glycopeptide Array

Z Biotech’s SARS-CoV-2 Receptor-Binding Domain (RBD) Peptide and Glycopeptide Array allows researchers to identify, profile, and compare specific IgG, IgA, and IgM antibody responses or detect and validate protein interactions with various RBD sequences in a customizable format. 

Researchers can choose from a list of 83 15-mer WT and mutant RBD peptide sequences, including sequences from the Alpha, Beta, Gamma, Delta, Omicron, and other SARS-CoV-2 variants. Four glycopeptides have been added to the list. The selected sequences are immobilized on a glass slide using our proprietary multivalent surface coating technology, which minimizes background and maximizes sensitivity.

Peptides

Benefits:

• Highly customizable
  
• Low background
  
• High sensitivity
  
• Only a small sample volume required
  
• Simple assay format
  
• Very affordable
  
• Assay service available
  
  

List of peptides and glycopeptides for custom microarrays; additional peptides and glycopeptides available upon request. 

Applications:

• Profile antibody responses from patient or animal sera
  
• Screen and characterize immunodominant RBD epitopes
  
• Compare antibody responses across various RBD mutants
  
• Identify RBD-interacting proteins